Larry R. Aaronson, Ph.D.
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Biography
A native Floridian, I earned a B.S. 1979年在佛罗里达州立大学获得生物科学学位. In 1984 I received a Ph.D. 在Rutgers University的微生物学专业,我研究了真菌在冷适应过程中膜流动性的调节. Charles Martin. Later, 我在耶鲁大学医学院人类遗传学系做博士后时,跟随Dr . .研究真菌质膜质子泵的生物发生. Carolyn Slayman. I joined the faculty of UticaCollege in 1987, and teach Principles of Microbiology, Molecular Biology, Immunology, and Virology, among other courses.
An advocate for undergraduate research, 我目前是本科研究委员会的生物学委员,也是美国微生物学会本科教育委员会的成员,在那里我领导了新的本科教学奖学金计划. 1996年,我在加州大学获得了Crisafulli杰出教学奖和Harold T. Clark Award for Research in 1997. In 2007, 我获得了美国微生物学会/卡斯基基金会杰出本科教学奖. (http://www.asm.org/Academy/index.asp?bid=39527)
My hobbies include reading biomedical thrillers, rose gardening, making and throwing boomerangs, and all things Star Trek.
Opportunities for Student Research and Collaboration
Over the past 23 years, 多达60名尤蒂卡学院的学生和18名当地高中的学生在我的实验室做过研究项目. 这些学生中有许多人在国家科学会议上发表过论文, 并获得了美国微生物学会的资助和奖学金, 美国显微镜学会和Sigma Xi支持他们的研究. 我研究小组的一些学生后来在耶鲁大学等机构获得了研究生学位, George Washington University, Penn State, University of Pittsburgh, University of Maryland, University of Rochester, University of Alabama – Birmingham, Mayo School of Medicine and Howard University.
Education
B.S. in Biological Sciences from Florida State University (1979)
Ph.D. in Microbiology from Rutgers University (1984)
耶鲁大学医学院人类遗传学系招收博士后. Carolyn Slayman
Past Research
我目前的研究兴趣集中在动物皮肤中天然抗真菌防御的研究. 在过去的15年里,我的实验室小组一直专注于研究鞘脂的抗真菌特性, which may create a natural antifungal barrier in the skin. 这些研究可能会发现新的药物来对抗由真菌病原体引起的致命感染. 其他正在进行的项目包括对红背蝾螈抗真菌菌群的调查, 以及尤蒂卡沼泽受多氯联苯污染的沉积物中细菌的生物多样性. 新项目包括诱导蜡样芽孢杆菌的群体活动, and photoregulation of melanin production in Pseudomonas sp. UC17F4.
Most Recent Research Publications
Gerlach, J.A. , Bart, K.M., and Aaronson, L.R. 1997. 鞘氨氨酸对粗神经孢子虫线粒体活性和形态的影响. Microscopy and Microanalysis 3: 69.
Gerlach, J.A., Bart, K.M., and Aaronson, L.R. 2001. 鞘氨氨酸诱导粗神经孢子虫的渗透不稳定和膜通透性增加. (Submitted for Publication.)
van Kessel, J.C., Scanlon, T.L., and Aaronson, L.R. 2003. 红背蝾螈皮肤抗真菌菌群的鉴定, Plethodon cinereus. (Submitted to Microbial Ecology; in review)
Aaronson, L.R. 2008. “新颖的方法”:通俗小说作为本科微生物学课程的教学工具. Focus on Microbiology Education 15: 2-4.
Recent Meeting Presentations (student authors in boldface)
Mikalajunas, D.M. , Van Slyke, G.M., and Aaronson, L.R. 2000. Biotin transport in Neurospora crassa. 美国微生物学会第100届大会摘要.
Taylor, D.G. , Augusto, S.S., Bart, K.M., and Aaronson, L.R. 2001. 鞘鞘烷的抗菌特性:载体影响毒性. 美国微生物学会第101届全体会议摘要,第2页. 39.
McGovern, E.M., van Kessel, J.C., Scanlon, T.L., Pilla, A.E., and Aaronson, L.R. 2002. 粗神经孢子虫生物素转运缺陷突变体的分离与鉴定. Abstracts of the 102nd Gen. Mtg. of the Am. Soc. for Microbiol., pg. 504
van Kessel, J.C., Scanlon, T.L., and Aaronson, L.R. 2003. 红背蝾螈皮肤抗真菌菌群的鉴定, Plethodon cinereus. Abstracts of the 103rd Gen. Mtg. Of the Am. Soc. for Microbiol. pg. 435.
Aaronson, L.R. 2003. 科学与小说:为科学教育研究生开设的微生物学和分子生物学“小说”课程. Abstracts of the 103rd Gen. Mtg. Of the Am. Soc. for Microbiol. pg. 655.
Szymanska, E. and Aaronson, L.R. 2004. 大体解剖实验室中的微生物污染物:土曲菌的分离. and Pseudomonas fluorescens from a phenolic waste mop bucket. Abstracts of the 104th Gen. Mtg. Of the Am. Soc. for Microbiol. pg. 535.
Aaronson, L.R. 2005. “即将到来的瘟疫”:一个关于新出现的传染病的在线课程, 面向研究生教师教育和通识学生的生物武器与公共卫生. Abstracts of the 105th Gen. Mtg. Of the Am. Soc. for Microbiol.
Butler, A.M. and Aaronson, L.R. 2006. 两种未知抗真菌假单胞菌的鉴定及其对粗神经孢子菌菌丝形态的影响. Abstracts of the 106th Gen. Mtg. Of the Am. Soc. for Microbiol.
Butler, A.M. and Aaronson, L.R. 2007. 假单胞菌抗真菌分泌物通过假定的钙离子载体诱导粗神经孢子菌菌丝分支异常. Abstracts of the 107th Gen. Mtg. Of the Am. Soc. for Microbiol.
Szymanska, E., and Aaronson, L. R. 2007. Alteration of Candida albicans biofilm development by sphinganine. Abstracts of the 107th Gen. Mtg. Of the Am. Soc. for Microbiol.
Butler, A.M. and Aaronson, L.R. 2008. 在黄假单胞菌和荧光假单胞菌上清液中对真菌细胞进行四环素染色,进一步证明了钙离子载体的存在. Abstracts of the 108th Gen. Mtg. Of the Am. Soc. for Microbiol.
Szymanska, E. and Aaronson, L.R. 2008. 鞘氨氨酸对白色念珠菌生物膜形成的抑制作用:不同菌丝诱导培养基对ALS-1基因表达的抑制及差异敏感性. Abstracts of the 108th Gen. Mtg. Of the Am. Soc. for Microbiol.
Aaronson, L.R. 2008. 在本科微生物学课程中运用通俗小说,促进知识的学习与整合. Abstracts of the 15th Annual Am. Soc. for Microbiol. Conference for Undergraduate Educators, pg. 84.
St. Louis, M.L., Cortese A., and Aaronson, L.R. 2010 Induction of Apoptosis in Candida albicans by Sphinganine. 美国微生物学会第110届大会摘要
Galbraith, K.M., Bankowski, M., and Aaronson, L. R.. Inhibitory Effects of Sphinganine on Growth, Viability and Biofilm Formation in Staphylococcus aureus. 美国微生物学会第110届大会摘要
Courses Taught
BIO 432 - Principles of Microbiology
Survey of microbial groups including bacteria, viruses, fungi, protists, and some invertebrate parasites. 细菌结构,生理学,遗传学,感染和疾病,免疫反应. Laboratory experience in isolation, culturing, morphological and biochemical characterization and identification; chemical and physical control of microbial growth.
BIO 454 - Immunology
Advanced study of the immune system in animals. Emphasis on immunochemistry, cellular immunity, immunopathology, and role of immune system in transplantation, cancer, and AIDS.
BIO 455 – Virology
Biology of bacterial, plant and animal viruses. 病毒结构,感染和复制周期,病毒-宿主相互作用. Role of viruses in infectious disease and cancer. Viruses as vehicles in biotechnology and gene therapy.
CHE 463 - Biochemistry II
Biological Membranes and Transport, Biosignaling, Metabolic Regulation, Urea Cycle, Biosynthesis of Amino Acids, Lipid Biosynthesis, Oxidative and Photophosphorylation, Integration of Metabolism.
BIO 528 - Science and Fiction
通俗小说、电影和视频作为生物学教学工具.
BIO 654 -“即将到来的瘟疫”:新出现的传染病、生物武器和公共卫生
人类活动对通过自然和人工手段出现的新传染原的影响, and the consequences for global public health and economics.
Awards and Recognition
Crisafulli Distinguished Teaching Award (1996)
Harold T. Clark Award for Research (1997)
美国微生物学会/卡斯基基金会杰出本科教学奖(2007)
Harold T. Clark, Jr. Professor of Microbiology (2010 - 2015)
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